Infrared Coagulator™: A Useful Tool for Treating Anal Squamous Intraepithelial Lesions

@article{Goldstone2005InfraredCA,
  title={Infrared Coagulator{\texttrademark}: A Useful Tool for Treating Anal Squamous Intraepithelial Lesions},
  author={Stephen E Goldstone and Adam Z Kawalek and Jeff W Huyett},
  journal={Diseases of the Colon \& Rectum},
  year={2005},
  volume={48},
  pages={1042-1054}
}
PURPOSEThe incidence of invasive anal squamous carcinoma in men who have sex with men is rising, particularly in those with human immunodeficiency virus. As in the cervix the high-grade squamous intraepithelial lesion is thought to be an invasive squamous cell carcinoma precursor. Cervical high-grade squamous intraepithelial lesions are treated by removing the squamocolumnar transition zone. This is not possible in the anus, where treatment is often surgical and is accompanied by significant… 
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HRA-targeted surgical therapy coupled with surveillance and re-treatment with office-based therapies offered an effective method in controlling anal dysplasia in the immunocompetent patient.
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TLDR
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TLDR
Patients undergoing ablation of intra-anal high-grade dysplasia have high recurrence, but the probability of developing anal cancer is low, and HIV infection and increased number of high- grade dysplasias increases the risk of recurrence.
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TLDR
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