• Corpus ID: 209515720

Information costs in the control of protein synthesis.

@article{Rousseau2019InformationCI,
  title={Information costs in the control of protein synthesis.},
  author={Rebecca J. Rousseau and William Bialek},
  journal={arXiv: Subcellular Processes},
  year={2019}
}
Efficient protein synthesis depends on the availability of charged tRNA molecules. With 61 different codons, shifting the balance among the tRNA abundances can lead to large changes in the protein synthesis rate. Previous theoretical work has asked about the optimization of these abundances, and there is some evidence that regulatory mechanisms bring cells close to this optimum, on average. We formulate the tradeoff between the precision of control and the efficiency of synthesis, asking for… 

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