Influenza virus ns1 protein induces apoptosis in cultured cells.

  title={Influenza virus ns1 protein induces apoptosis in cultured cells.},
  author={Stacy Schultz-Cherry and Naomi Dybdahl-Sissoko and Gabriele Neumann and Yoshihiro Kawaoka and Virginia S. Hinshaw},
  journal={Journal of virology},
  volume={75 17},
The importance of influenza viruses as worldwide pathogens in humans, domestic animals, and poultry is well recognized. Discerning how influenza viruses interact with the host at a cellular level is crucial for a better understanding of viral pathogenesis. Influenza viruses induce apoptosis through mechanisms involving the interplay of cellular and viral factors that may depend on the cell type. However, it is unclear which viral genes induce apoptosis. In these studies, we show that the… CONTINUE READING

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