Influenza vaccines: the virosome concept.

@article{Wilschut2009InfluenzaVT,
  title={Influenza vaccines: the virosome concept.},
  author={Jan C. Wilschut},
  journal={Immunology letters},
  year={2009},
  volume={122 2},
  pages={118-21}
}
Influenza virosomes are virus-like particles, which retain the cell binding and membrane fusion properties of the native virus, but lack the viral genetic material. These functional characteristics of influenza virosomes form the basis for their immunogenicity. First, the repetitive arrangement of the major viral envelope glycoprotein, haemagglutinin, on the virosomal surface mediates a co-operative interaction with Ig receptors on B lymphocytes, stimulating strong antibody responses. In… CONTINUE READING

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