Influenza Virus Hemagglutinin Glycoproteins with Different N-Glycan Patterns Activate Dendritic Cells In Vitro.

@article{Liu2016InfluenzaVH,
  title={Influenza Virus Hemagglutinin Glycoproteins with Different N-Glycan Patterns Activate Dendritic Cells In Vitro.},
  author={Wen-chun Liu and Yu-Li Lin and Maureen A. Spearman and Pei-Yun Cheng and Michael Butler and Suh-Chin Wu},
  journal={Journal of virology},
  year={2016},
  volume={90 13},
  pages={6085-6096}
}
UNLABELLED Influenza virus hemagglutinin (HA) N-glycans play important regulatory roles in the control of virus virulence, antigenicity, receptor-binding specificity, and viral escape from the immune response. Considered essential for controlling innate and adaptive immune responses against influenza virus infections, dendritic cells (DCs) trigger proinflammatory and adaptive immune responses in hosts. In this study, we engineered Chinese hamster ovary (CHO) cell lines expressing recombinant HA… CONTINUE READING
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