Influenza RNA not detected in archival brain tissues from acute encephalitis lethargica cases or in postencephalitic Parkinson cases.

@article{McCall2001InfluenzaRN,
  title={Influenza RNA not detected in archival brain tissues from acute encephalitis lethargica cases or in postencephalitic Parkinson cases.},
  author={Sherman A. McCall and James M. Henry and Ann H. Reid and Jeffery K. Taubenberger},
  journal={Journal of neuropathology and experimental neurology},
  year={2001},
  volume={60 7},
  pages={
          696-704
        }
}
Encephalitis lethargica (EL) was a mysterious epidemic. temporally associated with the 1918 Spanish influenza pandemic. Numerous symptoms characterized this disease, including headache, diplopia, fever, fatal coma, delirium, oculogyric crisis, lethargy, catatonia, and psychiatric symptoms. Many patients who initially recovered subsequently developed profound, chronic parkinsonism. The etiologic association of influenza with EL is controversial. Five acute EL autopsies and more than 70… CONTINUE READING