Influenza NS1 interacts with p53 and alters its binding to p53-responsive genes, in a promoter-dependent manner.

Abstract

The interplay between influenza A viruses (IAV) and p53 has only been reported in a limited number of studies, mainly focusing on the antiviral role of p53. We investigated the impact of IAV infection on p53 stability and transcriptional activity. Our results indicate that IAV-induced stabilization of p53 only partially correlates with modulation of p53… (More)
DOI: 10.1016/j.febslet.2013.08.006

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