Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes.

@article{Yewdell1985InfluenzaAV,
  title={Influenza A virus nucleoprotein is a major target antigen for cross-reactive anti-influenza A virus cytotoxic T lymphocytes.},
  author={Jonathan W. Yewdell and Jack R. Bennink and Geoffrey L Smith and Bernard Moss},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1985},
  volume={82 6},
  pages={
          1785-9
        }
}
Influenza A virus-specific cytotoxic T lymphocytes (CTL) capable of lysing cells infected with any influenza A virus ("cross-reactive CTL") constitute a major portion of the host CTL response to influenza. The viral nucleoprotein (NP), a major internal virion structural protein, has been implicated as a possible target antigen for cross-reactive CTL. To directly examine CTL recognition of NP, a vaccinia virus recombinant containing a DNA copy of an influenza A virus NP gene was constructed. We… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 200 CITATIONS

FILTER CITATIONS BY YEAR

1984
2019

CITATION STATISTICS

  • 6 Highly Influenced Citations

  • Averaged 7 Citations per year over the last 3 years

  • 25% Increase in citations per year in 2018 over 2017

Similar Papers

Loading similar papers…