Influenza A Virus Induces an Immediate Cytotoxic Activity in All Major Subsets of Peripheral Blood Mononuclear Cells

@article{turlan2009InfluenzaAV,
  title={Influenza A Virus Induces an Immediate Cytotoxic Activity in All Major Subsets of Peripheral Blood Mononuclear Cells},
  author={Sanda {\vS}turlan and Monika Sachet and Suzann Baumann and Irina Kuznetsova and Andreas Spittler and Michael Bergmann},
  journal={PLoS ONE},
  year={2009},
  volume={4},
  pages={517 - 523}
}
BACKGROUND A replication defective influenza A vaccine virus (delNS1 virus) was developed. Its attenuation is due to potent stimulation of the innate immune system by the virus. Since the innate immune system can also target cancer cells, we reasoned that delNS1 virus induced immune-stimulation should also lead to the induction of innate cytotoxic effects… CONTINUE READING