Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population

Abstract

Polymorphisms in dopaminergic genes may influence cigarette smoking by their potential impact on dopamine reward pathway function. A1 allele of DRD2 gene is associated with a reduced dopamine D2 receptor density, and it has been hypothesised that A1 carriers are more vulnerable to smoking. In turn, the 9-repeat allele of dopamine transporter gene (SLC6A3… (More)
DOI: 10.1186/1471-2350-10-92

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@article{Siemiska2008InfluencesOP, title={Influences of polymorphic variants of DRD2 and SLC6A3 genes, and their combinations on smoking in Polish population}, author={Alicja Siemińska and Krzysztof Buczkowski and Ewa Jassem and Marek Niedoszytko and Ewa Tkacz}, journal={BMC Medical Genetics}, year={2008}, volume={10}, pages={92 - 92} }