Influences of membrane mimetic environments on membrane protein structures.

@article{Zhou2013InfluencesOM,
  title={Influences of membrane mimetic environments on membrane protein structures.},
  author={Huan-Xiang Zhou and Timothy A. Cross},
  journal={Annual review of biophysics},
  year={2013},
  volume={42},
  pages={
          361-92
        }
}
The number of membrane protein structures in the Protein Data Bank is becoming significant and growing. Here, the transmembrane domain structures of the helical membrane proteins are evaluated to assess the influences of the membrane mimetic environments. Toward this goal, many of the biophysical properties of membranes are discussed and contrasted with those of the membrane mimetics commonly used for structure determination. Although the mimetic environments can perturb the protein structures… CONTINUE READING
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