Influences of dietary energy and protein on leucine kinetics during feeding in healthy adults.

@article{Gibson1996InfluencesOD,
  title={Influences of dietary energy and protein on leucine kinetics during feeding in healthy adults.},
  author={Neil R Gibson and Amelia Fereday and Malcolm Cox and David F. Halliday and Paul J Pacy and Douglas Millward},
  journal={The American journal of physiology},
  year={1996},
  volume={270 2 Pt 1},
  pages={E282-91}
}
Ten adult men were infused with L-[1-13C]leucine for 9 h commencing in the postabsorptive state (PA, 0-3 h), during the half-hourly feeding of low-protein meals (LP, protein = 2% calories, 3-6 h), and during feeding isoenergetic high-protein meals (HP, protein = 14% calories, 6-9 h). Leucine oxidation and turnover (protein synthesis and degradation) were determined from plasma alpha-[1-13C]ketoisocaproate enrichment and expired 13CO2 excretion measured during the third hour of each 3-h period… CONTINUE READING