Influence on the electrocardiogram of rats by antidepressants.


The influence of lofepramine on the heart has been studied in anaesthetized rats. Lofepramine and other antidepressants were infused i.v. during 4 h at a rate of 0.5 mg/kg/min for lofepramine (equimolar concentrations for the other antidepressants). ECG and survival time were recorded. It was shown that lofepramine in contrast to the other antidepressants… (More)


Cite this paper

@article{Sjgren1987InfluenceOT, title={Influence on the electrocardiogram of rats by antidepressants.}, author={Christer Sj{\"{o}gren}, journal={Arzneimittel-Forschung}, year={1987}, volume={37 9}, pages={1017-20} }