Influence of zinc on Pseudomonas aeruginosa susceptibilities to imipenem.

  title={Influence of zinc on Pseudomonas aeruginosa susceptibilities to imipenem.},
  author={G L Cooper and Arnold Louie and Aldona L Baltch and R C Chu and Raymond P. Smith and William J Ritz and Peter Michelsen},
  journal={Journal of clinical microbiology},
  volume={31 9},
Serial dilution susceptibility testing of imipenem against 59 clinical isolates of Pseudomonas aeruginosa, conducted simultaneously on single lots of Difco and BBL Mueller-Hinton agar (MHA), resulted in MICs for 90% of strains tested of 8 and 16 micrograms/ml, respectively. MICs for Escherichia coli, Klebsiella pneumoniae, and Pseudomonas spp. were also higher on BBL MHA. Quantification of the cation content of the two MHAs by atomic absorption spectroscopy demonstrated that the zinc… CONTINUE READING


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