Influence of zinc deficiency on the mRNA expression of zinc transporters in adult rats.

@article{Pfaffl2003InfluenceOZ,
  title={Influence of zinc deficiency on the mRNA expression of zinc transporters in adult rats.},
  author={Michael W. Pfaffl and Wilhelm Windisch},
  journal={Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements},
  year={2003},
  volume={17 2},
  pages={97-106}
}
The accumulation of zinc in the cell is a sum of influx and efflux processes via transporter proteins, like the four Zn transporters (ZnT1-4), the divalent cation transporter 1 (DCT1) and of storage processes mainly bound to metallothionein (MT). To study the effect of Zn deficiency on mRNA expression levels, adult rats were used as an animal model. Food intake was restricted to 8 g/day containing 2 microg Zn/g fortified with pure phytate in Zn deficiency rats and 58 microg Zn/g in controls (n… CONTINUE READING

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