Influence of vitamins A, C, and E and beta-carotene on aflatoxin B1 binding to DNA in woodchuck hepatocytes.

@article{Yu1994InfluenceOV,
  title={Influence of vitamins A, C, and E and beta-carotene on aflatoxin B1 binding to DNA in woodchuck hepatocytes.},
  author={M W Yu and Yu Jing Zhang and William S. Blaner and Regina M. Santella},
  journal={Cancer},
  year={1994},
  volume={73 3},
  pages={596-604}
}
BACKGROUND There is extensive epidemiologic evidence suggesting a protective role for micronutrients in cancer incidence. This evidence comes from studies of fruit and vegetable intake and serum levels of specific micronutrients. There also is limited in vitro evidence demonstrating that micronutrients can influence the first step in carcinogenesis, binding of chemical carcinogens to DNA. These in vitro studies allow the determination of specific effects of individual micronutrients. The… CONTINUE READING