Influence of various doses of aspirin (in vivo) on platelet arachidonic acid metabolism (ex vivo) and function.

@article{Rao1994InfluenceOV,
  title={Influence of various doses of aspirin (in vivo) on platelet arachidonic acid metabolism (ex vivo) and function.},
  author={G. Rao and J. White},
  journal={Prostaglandins, leukotrienes, and essential fatty acids},
  year={1994},
  volume={51 1},
  pages={
          63-7
        }
}
  • G. Rao, J. White
  • Published 1994
  • Chemistry, Medicine
  • Prostaglandins, leukotrienes, and essential fatty acids
  • The influence of various doses of enteric-coated aspirin was evaluated for its in vivo effect on ex vivo platelet arachidonic acid metabolism and function. 24 h after ingestion of the drugs compromised platelet response to the action of agonists such as epinephrine and arachidonate could be demonstrated with as low a dose as 50 mgs aspirin. However, platelets with compromised function were still capable of producing significant quantities of thromboxane. On the other hand, platelets with almost… CONTINUE READING
    7 Citations

    Topics from this paper

    References

    SHOWING 1-10 OF 26 REFERENCES
    Influence of epinephrine on the aggregation response of aspirin-treated platelets.
    • 83
    A regimen for low-dose aspirin?
    • 53
    • PDF