Influence of variants of Fc gamma receptors IIA and IIIA on the American College of Rheumatology and European League Against Rheumatism responses to anti-tumour necrosis factor alpha therapy in rheumatoid arthritis.

@article{Caete2009InfluenceOV,
  title={Influence of variants of Fc gamma receptors IIA and IIIA on the American College of Rheumatology and European League Against Rheumatism responses to anti-tumour necrosis factor alpha therapy in rheumatoid arthritis.},
  author={Juan D. Ca{\~n}ete and Belen Prados Suarez and Mar{\'i}a Victoria Hern{\'a}ndez and Raimon Sanmart{\'i} and Ignacio Rego and Raquel Celis and Concepci{\'o}n Navarro Moll and Jos{\'e} Ant{\'o}nio Ara{\'u}jo Pinto and Francisco J Blanco and Francisco Lozano},
  journal={Annals of the rheumatic diseases},
  year={2009},
  volume={68 10},
  pages={
          1547-52
        }
}
OBJECTIVE Fc gamma receptor (Fc gammaR) polymorphism influences the affinity of the receptor for Ig, which may, in turn, affect the efficacy of Ig-based therapies. The relationship between functional single nucleotide polymorphisms (SNP) of the FCGR2A and FCGR3A genes and the response to anti-tumour necrosis factor (TNF)alpha therapy (infliximab) in patients with rheumatoid arthritis (RA) was assessed. METHODS A total of 91 patients with RA (89% female; 76.7% rheumatoid factor (RF) positive… CONTINUE READING
BETA

Citations

Publications citing this paper.
SHOWING 1-10 OF 38 CITATIONS

Similar Papers

Loading similar papers…