Influence of usual intake of dietary caffeine on single-dose kinetics of theophylline in healthy human subjects

@article{Sato1993InfluenceOU,
  title={Influence of usual intake of dietary caffeine on single-dose kinetics of theophylline in healthy human subjects},
  author={Juichi Sato and Hideyuki Nakata and Eiji Owada and Toshiteru Kikuta and Masao Umetsu and Kiyomi Ito},
  journal={European Journal of Clinical Pharmacology},
  year={1993},
  volume={44},
  pages={295-298}
}
The influence of usual multiple ingestions of dietary caffeine on oral single-dose pharmacokinetics of theophylline has been investigated in 6 healthy male subjects. The subjects consumed 2 to 7 cups of regular instant coffee during the 24 h study period. Their mean serum concentrations of caffeine varied from 1.2 to 3.1 mg/l. After their usual intake of… CONTINUE READING