Influence of tumour size on human prostate tumour metastasis in athymic nude mice.

@article{Ware1985InfluenceOT,
  title={Influence of tumour size on human prostate tumour metastasis in athymic nude mice.},
  author={Joy L. Ware and Elizabeth R. DeLong},
  journal={British Journal of Cancer},
  year={1985},
  volume={51},
  pages={419 - 423}
}
Human tumours which grow and metastasize in immunodeficient animals are amenable to controlled investigation of human tumour metastasis in the presence of the original tumour inoculum. In previous reports (Ware et al., 1982, 1984), we described a unique human prostate carcinoma subline, l-LN-PC-3-lA, which consistently metastasizes from a subcutaneous (s.c.) site to both regional and distant lymph nodes in tumour-excised adult athymic nude mice. These tumour cells also form multiple lung… CONTINUE READING

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