Influence of training paradigm on specificity of drug mixture discriminations.

@article{Mariathasan1999InfluenceOT,
  title={Influence of training paradigm on specificity of drug mixture discriminations.},
  author={E. A. Mariathasan and Ian P. Stolerman and J. A. Henton White},
  journal={Pharmacology, biochemistry, and behavior},
  year={1999},
  volume={64 2},
  pages={409-13}
}
Generalization to different drugs and drug mixtures has been examined in rats trained to discriminate a mixture of amphetamine (0.4 mg/kg) plus pentobarbitone (10 mg/kg) from saline (AND discrimination, n = 8) or to discriminate the same mixture from its component drugs alone (AND-OR discrimination, n = 9). The studies used two-lever operant procedures with… CONTINUE READING