Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats.

@article{Truettner2005InfluenceOT,
  title={Influence of therapeutic hypothermia on matrix metalloproteinase activity after traumatic brain injury in rats.},
  author={Jessie S. Truettner and Ofelia F. Alonso and W. Dalton Dietrich},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2005},
  volume={25 11},
  pages={1505-16}
}
Recent evidence suggests that matrix metalloproteinases (MMPs) contribute to acute edema and lesion formation following ischemic and traumatic brain injuries (TBI). Experimental and clinical studies have also reported the beneficial effects of posttraumatic hypothermia on histopathological and behavioral outcome. The purpose of this study was to determine whether therapeutic hypothermia would affect the activity of MMPs after TBI. Male Sprague-Dawley rats were traumatized by moderate… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 84 references

Matrix metalloproteinases limit functional recovery after spinal cord injury by modulation of early vascular events.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2002
View 6 Excerpts
Highly Influenced

Effects of matrix metalloproteinase-9 gene knock-out on the proteolysis of blood-brain barrier and white matter components after cerebral ischemia.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2001
View 4 Excerpts
Highly Influenced

The Rat Brain in Stereotaxic Coordinates

Trends in Neurosciences • 1984
View 1 Excerpt
Highly Influenced

Induction of caspase-mediated cell death by matrix metalloproteinases in cerebral endothelial cells after hypoxia-reoxygenation.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism • 2004

Similar Papers

Loading similar papers…