Influence of the thyroid state on myocardial myosin in the adult pig heart

  title={Influence of the thyroid state on myocardial myosin in the adult pig heart},
  author={Dr. med V. Wiegand and H. Henniges and R. Oberschmidt and Heinrich Kreuzer},
  journal={Basic Research in Cardiology},
The influence of hyper- and hypothyroidism on atrial and ventricular myosin structure and Ca2+-activated ATPase activity has been analyzed in adult mini-pigs. Whereas no difference could be demonstrated between hypo- and euthyroid ventricular myocardium, Ca2+-activated ATPase activity was significantly higher in the hyperthyroid than in the hypo- or euthyroid state. Using pyrophosphate electrophoresis and isoelectric focusing of subfragment 1 this could be ascribed to an additional ventricular… CONTINUE READING
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