Influence of the respirator on volatile organic compounds: an animal study in rats over 24 hours.

@article{Albrecht2015InfluenceOT,
  title={Influence of the respirator on volatile organic compounds: an animal study in rats over 24 hours.},
  author={Frederic W Albrecht and Tobias H{\"u}ppe and Tobias Fink and Felix Maurer and Alexander Wolf and Beate Wolf and Thomas Volk and J{\"o}rg Ingo Baumbach and Sascha Kreuer},
  journal={Journal of breath research},
  year={2015},
  volume={9 1},
  pages={016007}
}
Long-term animal studies are needed to accomplish measurements of volatile organic compounds (VOCs) for medical diagnostics. In order to analyze the time course of VOCs, it is necessary to ventilate these animals. Therefore, a total of 10 male Sprague-Dawley rats were anaesthetized and ventilated with synthetic air via tracheotomy for 24 h. An ion mobility spectrometry coupled to multi-capillary columns (MCC-IMS) was used to analyze the expired air. To identify background contaminations… CONTINUE READING
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