Influence of the membrane potential on the free energy of an intrinsic protein.

@article{Roux1997InfluenceOT,
  title={Influence of the membrane potential on the free energy of an intrinsic protein.},
  author={Beno{\^i}t Roux},
  journal={Biophysical journal},
  year={1997},
  volume={73 6},
  pages={2980-9}
}
A modified Poisson-Boltzmann equation is developed from statistical mechanical considerations to describe the influence of the transmembrane potential on macromolecular systems. Using a Green's function formalism, the electrostatic free energy of a protein associated with the membrane is expressed as the sum of three terms: a contribution from the energy required to charge the system's capacitance, a contribution corresponding to the interaction of the protein charges with the membrane… CONTINUE READING

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