Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: the Lyon R90-01 randomized trial.

@article{Franois1999InfluenceOT,
  title={Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: the Lyon R90-01 randomized trial.},
  author={Yves François and Chantal N{\'e}moz and Jacques Baulieux and Jacques Vignal and Jean Paul Grandjean and Christian Partensky and J. C. Souquet and Patrice Adeleine and Jean Pierre G{\'e}rard},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1999},
  volume={17 8},
  pages={2396}
}
PURPOSE The optimal timing of surgery after preoperative radiotherapy in rectal cancer is unknown. The aim of this trial was to evaluate the role of the interval between preoperative radiotherapy and surgery. PATIENTS AND METHODS Patients with rectal carcinoma accessible to rectal digital examination, staged T2 to T3, NX, M0, were randomized before… CONTINUE READING