Influence of the hypothalamic-pituitary-adrenal axis dysregulation on the metabolic profile of patients affected by diabetes mellitus-associated late onset hypogonadism.

@article{Tirabassi2016InfluenceOT,
  title={Influence of the hypothalamic-pituitary-adrenal axis dysregulation on the metabolic profile of patients affected by diabetes mellitus-associated late onset hypogonadism.},
  author={Giacomo Tirabassi and Francesco Chelli and Mariateresa Ciommi and Andrea Lenzi and Giancarlo Balercia},
  journal={Nutrition, metabolism, and cardiovascular diseases : NMCD},
  year={2016},
  volume={26 1},
  pages={53-9}
}
BACKGROUND AND AIMS Functional hypercortisolism (FH) is generated by clinical states able to chronically activate the hypothalamic-pituitary-adrenal (HPA) axis [e.g. diabetes mellitus (DM)]. No study has evaluated FH influence in worsening the metabolic profile of male patients affected by DM-associated hypogonadism. In this retrospective work, we assess the possible association between HPA axis-dysregulation and cardiovascular risk factors in men simultaneously affected by DM and late-onset… CONTINUE READING
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