Influence of the fibroblast environment on the structure of mast cell proteoglycans.

The structure of the proteoglycan synthesized by rodent mast cells has been a useful biochemical marker of mast cell subpopulations, since mucosal mast cells synthesize predominantly oversulfated chondroitin sulfate proteoglycan and connective tissue mast cells synthesize heparin proteoglycan. Mast cells are intimately associated with fibroblasts in tissues… CONTINUE READING