Influence of the extent of resection on survival after curative treatment of gastric carcinoma. A retrospective multivariate analysis.

Abstract

The therapeutic value of extensive gastric resection and regional lymphadenectomy in the curative treatment of gastric adenocarcinoma is controversial. We undertook a retrospective study of 210 patients treated with curative intent from 1960 to 1980. A multivariate survival analysis using the Cox model revealed five significant variables predictive of death from gastric cancer--two inherent pathologic factors: (1) nonpyloric site and (2) metastases in more than three lymph nodes, and three treatment factors that could often be controlled by the surgeon: (3) microscopic positive gastric resection margin, (4) inadequate lymphadenectomy, and (5) total gastrectomy. These observations reaffirm the value of wide gastric resection and adequate lymphadenectomy but argue against a general policy of elective total gastrectomy in the curative treatment of gastric carcinoma.

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@article{Shiu1987InfluenceOT, title={Influence of the extent of resection on survival after curative treatment of gastric carcinoma. A retrospective multivariate analysis.}, author={M. H. Shiu and Ernest Eugene Moore and Melissa R. Sanders and Andrew S. Huvos and Ben S Freedman and J Goodbold and S Chaiyaphruk and R. I. C. Wesdorp and Murray F. Brennan}, journal={Archives of surgery}, year={1987}, volume={122 11}, pages={1347-51} }