Influence of the C-terminal residues on oligomerization of alpha A-crystallin.

@article{Thampi2003InfluenceOT,
  title={Influence of the C-terminal residues on oligomerization of alpha A-crystallin.},
  author={Prajitha Thampi and Edathara C. Abraham},
  journal={Biochemistry},
  year={2003},
  volume={42 40},
  pages={11857-63}
}
Earlier studies have shown that the chaperone activity of alpha-crystallin is significantly affected in diabetic rat and human lenses. Subsequently, mass spectrometric analysis showed diabetic lenses having high levels of the alphaA-crystallins in which different numbers of C-terminal residues were deleted. The present study was aimed to show whether… CONTINUE READING