Influence of temperature and adrenergic stimulation on rat sinoatrial frequency.

@article{Bolter1988InfluenceOT,
  title={Influence of temperature and adrenergic stimulation on rat sinoatrial frequency.},
  author={C. P. Bolter and K. Atkinson},
  journal={The American journal of physiology},
  year={1988},
  volume={254 5 Pt 2},
  pages={R840-4}
}
We examined the effect of temperature and adrenergic stimulation on atrial rate in the rat. Right atrial preparations were maintained for 65 min at 38.0 degrees C and then exposed to high or moderate concentrations of isoproterenol (ISO) or left as controls. Temperature was cycled through four different values between 35.6 and 42.8 degrees C and allowed to stabilize at each value before atrial rate was measured. The rate-temperature loops exhibited a modest hysteresis; higher values for rate… CONTINUE READING