Influence of surveillance renal allograft biopsy on diagnosis and prognosis of polyomavirus-associated nephropathy.

@article{Buehrig2003InfluenceOS,
  title={Influence of surveillance renal allograft biopsy on diagnosis and prognosis of polyomavirus-associated nephropathy.},
  author={Christopher K Buehrig and Donna J. Lager and Mark D. Stegall and Michelle A Kreps and Walter Karl Kremers and James M. Gloor and T R Schwab and Jorge A. Velosa and Mary E. Fidler and Timothy S. Larson and Matthew D Griffin},
  journal={Kidney international},
  year={2003},
  volume={64 2},
  pages={
          665-73
        }
}
BACKGROUND Polyomavirus-associated nephropathy (PVAN) is an increasingly prevalent cause of allograft dysfunction. METHODS In 18 histologically proven cases of PVAN managed by reduced immunosuppression, monitoring of serum creatinine, and repeated biopsy, graft outcomes were correlated with clinical and histologic indices. Six months postdiagnosis the status of each graft was classified as poor (N = 7) or satisfactory (N = 11). Poor transplant status was defined as graft loss, increased… CONTINUE READING
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