Corpus ID: 29766439

Influence of substituted phenethylamines on lipolysis, in vitro. III. Stereoselectivity.

  title={Influence of substituted phenethylamines on lipolysis, in vitro. III. Stereoselectivity.},
  author={O. Lee and G. Bescak and D. Miller and D. Feller},
  journal={The Journal of pharmacology and experimental therapeutics},
  volume={190 2},
  • O. Lee, G. Bescak, +1 author D. Feller
  • Published 1974
  • Chemistry, Medicine
  • The Journal of pharmacology and experimental therapeutics
Investigations were undertaken to establish the steric interaction of phenethylamines on the release of glycerol from rat adipose tissue, in vitro . Primary emphasis was placed upon stereoselectivity at the asymmetric α-and/or β-carbon of the ethylamino side chain. Both stereoisomers of norepinephrine, α-methyldopamine, nordefrin, metaraminol and soterenol were found to increase glycerol release, whereas the isomers of ephedrine, norephedrine, amphetamine, methamphetamine and p… Expand
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