Influence of stress magnitude on water loss and chondrocyte viability in impacted articular cartilage.

@article{Milentijevic2003InfluenceOS,
  title={Influence of stress magnitude on water loss and chondrocyte viability in impacted articular cartilage.},
  author={Dejan Milentijevic and David L Helfet and Peter A. Torzilli},
  journal={Journal of biomechanical engineering},
  year={2003},
  volume={125 5},
  pages={594-601}
}
The objective of this study was to assess mechano-biological response of articular cartilage when subjected to a single impact stress. Mature bovine cartilage explants were impacted with peak stresses ranging from 10 to 60 MPa at a stress rate of 350 MPa/s. Water loss, matrix axial deformation, dynamic impact modulus (DIM), and cell viability were measured immediately after impaction. The water loss through the articular surface (AS) was small and ranged from 1% to 6% with increasing peak… CONTINUE READING
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