Influence of stem-cell cycle time on accelerated re-population during radiotherapy in head and neck cancer.

Abstract

OBJECTIVES Tumour re-population during radiotherapy was identified as an important reason for treatment failure in head and neck cancers. The process of re-population is suggested to be caused by various mechanisms, one of the most plausible one being accelerated division of stem-cells (i.e. drastic shortening of cell cycle duration). However, the… (More)
DOI: 10.1111/j.1365-2184.2012.00832.x

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