Influence of size at birth on the endocrine profiles and expression of uncoupling proteins in subcutaneous adipose tissue, lung, and muscle of neonatal pigs.

@article{Mostyn2005InfluenceOS,
  title={Influence of size at birth on the endocrine profiles and expression of uncoupling proteins in subcutaneous adipose tissue, lung, and muscle of neonatal pigs.},
  author={Alison Mostyn and Jennie C Litten and Katharine S Perkins and Philippa J Euden and Anne M Corson and Michael E Symonds and Lynne Clarke},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2005},
  volume={288 6},
  pages={R1536-42}
}
Epidemiological studies suggest that infants of low birth weight show poor neonatal growth and increased susceptibility to adult diseases such as diabetes and lung disease. Uncoupling protein 2 and 3 (UCP2 and UCP3) have been implicated in the development of such diseases; pigs provide an ideal model to examine the influence of birth weight due to the natural variance in piglet weight within a litter. This study examined whether birth weight influences the expression of UCP2 and UCP3 in adipose… CONTINUE READING

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