Influence of shell properties on high-frequency ultrasound imaging and drug delivery using polymer-shelled microbubbles

@article{Chitnis2013InfluenceOS,
  title={Influence of shell properties on high-frequency ultrasound imaging and drug delivery using polymer-shelled microbubbles},
  author={Parag V. Chitnis and Sujeethraj Koppolu and Jonathan Mamou and C. Chlon and J. A. Ketterling},
  journal={IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control},
  year={2013},
  volume={60}
}
This two-part study investigated shell rupture of ultrasound contrast agents (UCAs) under static overpressure conditions and the subharmonic component from UCAs subjected to 20-MHz tonebursts. Five different polylactide-shelled UCAs with shell-thickness-to-radius ratios (STRRs) of 7.5, 30, 40, 65, and 100 nm/¿m were subjected to static overpressure in a glycerol-filled test chamber. A video microscope imaged the UCAs as pressure varied from 2 to 330 kPa over 90 min. Images were postprocessed to… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 51 references

Buckling of empty spherical viruses under external pressure

  • c. q. ru
  • J. Appl. Phys., vol. 105, no. 12, art. no. 124701…
  • 2009
2 Excerpts

Similar Papers

Loading similar papers…