Influence of serotonin on the immune response.

  title={Influence of serotonin on the immune response.},
  author={J Craig Jackson and Ren{\'e} Cross and Richard N. Walker and William R. Markesbery and William H. Brooks and Thomas L. Roszman},
  volume={54 3},
The present study investigates the influence of pharmacological agents known to regulate biosynthesis of the neurotransmitter, serotonin (5-hydroxytryptamine, 5-HT) on the primary antibody response to sheep red blood cells (SRBC) in the CBA mouse. Systemic administration of 5-HT (4-100 mg/kg) or its precursor, 5-hydroxytryptophan (5-HTP, 50-400 mg/kg), 30-60 min before immunization resulted in dose-dependent suppression of both the IgM and IgG plaque-forming cell (PFC) response to SRBC… CONTINUE READING


Publications citing this paper.
Showing 1-10 of 16 extracted citations

Mammary gland serotonin regulates parathyroid hormone-related protein and other bone-related signals.

American journal of physiology. Endocrinology and metabolism • 2012
View 13 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…