Influence of replacing tuberculin skin test with ex vivo interferon γ release assays on decision to administer prophylactic antituberculosis antibiotics before anti-TNF therapy.

@article{Mariette2012InfluenceOR,
  title={Influence of replacing tuberculin skin test with ex vivo interferon γ release assays on decision to administer prophylactic antituberculosis antibiotics before anti-TNF therapy.},
  author={Xavier Mariette and Gabriel Bernardes Baron and Florence Tubach and Fr{\'e}d{\'e}ric Liot{\'e} and Bernard G Combe and Corinne Miceli-Richard and Ren{\'e}-Marc Flipo and Philippe Goupille and Matthieu Allez and D Salmon and Dominique Emilie and Guislaine Carcelain and Philippe Ravaud},
  journal={Annals of the rheumatic diseases},
  year={2012},
  volume={71 11},
  pages={
          1783-90
        }
}
BACKGROUND The recommendations for detecting latent tuberculosis infection (LTBI) before antitumour necrosis factor (anti-TNF) therapy are based on the tuberculin skin test (TST), which lacks both specificity and sensitivity and can lead to unnecessary treatment with antibiotics. A study was undertaken to investigate the effect of replacing TST with interferon γ (IFNγ) release assays (IGRA) in screening for LTBI and deciding to begin prophylactic antituberculosis (TB) antibiotics before anti… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 31 REFERENCES

Performance of two commercial blood IFN-γ release assays for the detection of Mycobacterium tuberculosis infection in patient candidates for anti-TNF-α treatment

M. Bocchino, A. Matarese, +10 authors A. Sanduzzi
  • European Journal of Clinical Microbiology & Infectious Diseases
  • 2008