Influence of recipient and donor IL-10, TNFA and INFG genotypes on the incidence of acute renal allograft rejection

@article{Azarpira2008InfluenceOR,
  title={Influence of recipient and donor IL-10, TNFA and INFG genotypes on the incidence of acute renal allograft rejection},
  author={Negar Azarpira and Mahdokht H. Aghdai and Ghanbar A. Raisjalali and Masumeh Darai and Moham J. Tarahi},
  journal={Molecular Biology Reports},
  year={2008},
  volume={36},
  pages={1621-1626}
}
Objective Transplantation of renal grafts is an established treatment for renal failure in a variety of medical conditions. Acute allograft rejection remains an important cause of morbidity after kidney transplantation, and has been shown to be a crucial determinant of long-term graft function. Although rejection is mediated by recipient lymphocytes, both donor and recipient factors contribute to the local environment that influences the severity of rejection response. Because cytokines are the… CONTINUE READING