Influence of pyrophosphate on the transformation of amorphous to crystalline calcium phosphate

  title={Influence of pyrophosphate on the transformation of amorphous to crystalline calcium phosphate},
  author={Herbert Andre Fleisch and R. Graham G. Russell and S. Bisaz and John D. Termine and Aaron S. Posner},
  journal={Calcified Tissue Research},
The transformation of amorphous calcium phosphate into its crystalline form has been studiedin vitro under various conditions. The transformation was followed by changes in the pH and in the calcium and phosphate content of the solution and by changes in the Ca/P ratio and x-ray diffraction patterns of the solid phase. It was found that inorganic pyrophosphate markedly increased the time required for the transformation under the various conditions used. The addition of intestinal alkaline… CONTINUE READING
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