Influence of protein on mannitol polymorphic form produced during co-spray drying.

@article{Hulse2009InfluenceOP,
  title={Influence of protein on mannitol polymorphic form produced during co-spray drying.},
  author={Wendy L. Hulse and Robert T M Forbes and Michael C Bonner and Matthias Getrost},
  journal={International journal of pharmaceutics},
  year={2009},
  volume={382 1-2},
  pages={67-72}
}
The stabilizing ability of the excipient on pharmaceutically relevant proteins for potential therapeutic use is an extensive area of research but the effect the protein has on the excipient is rarely reported. The influence of two model proteins on the polymorphic behaviour of mannitol during spray drying was therefore investigated. Spray dried mannitol/protein blends were characterised structurally using X-ray powder diffraction (XRPD) and Fourier transform Raman spectroscopy (FT-Raman) and… CONTINUE READING
7 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-7 of 7 extracted citations

Similar Papers

Loading similar papers…