Influence of primary diagnosis and complications on visual outcome in patients receiving a Boston type 1 keratoprosthesis.


PURPOSE To analyse how primary diagnosis and complications affect the evolution of post-operative visual acuity (VA). METHODS We performed retrospective chart analysis on 59 eyes in 57 patients with various diagnoses, most of which were non-standard indications for Boston type 1 keratoprosthesis (Kpro) implantation. The follow-up period was at least 3 months. Patients were classified based on the evolution of post-operative VA: group A demonstrated stable VA improvement, group B lost VA improvement and group C no significant VA improvement. RESULTS We assigned 46% of our cases to group A with stable VA improvement, 32% to group B with lost VA improvement, and 22% to group C with no VA improvement. The number of graft failures before Kpro implantation did not influence VA outcome. Except for the relatively good VA outcome in chemical burn and radiation injury patients, there seems to be no association between primary diagnosis and positive or negative VA outcome. Only 9% of patients with posterior segment complications and 20% with infections and associated pathologies were assigned to group A. CONCLUSION Most cases (78%) showed improvement in VA after Boston type 1 Kpro (groups A and B). Posterior segment complications and infections mostly resulted in persistent loss of vision. These complications should be prevented and carefully treated.

DOI: 10.1159/000358332

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@article{Nascimento2014InfluenceOP, title={Influence of primary diagnosis and complications on visual outcome in patients receiving a Boston type 1 keratoprosthesis.}, author={Valeria de Rezende Couto Nascimento and Mar{\'i}a Fid{\'e}liz de la Paz and Jurja Rosandi{\'c} and Josef Stoiber and Orang Seyeddain and G{\"{u}nther Grabner and Juan P {\'A}lvarez de Toledo and Rafael Ignacio Barraquer and Ralph Michael}, journal={Ophthalmic research}, year={2014}, volume={52 1}, pages={9-16} }