Influence of prednisolone on the secretion of mucin from the HT29-MTX cell line.

@article{Fergie2003InfluenceOP,
  title={Influence of prednisolone on the secretion of mucin from the HT29-MTX cell line.},
  author={Neil Fergie and Lian-Jun Guo and Jabolani Sithole and Jeffrey Peter Pearson and John P. Birchall},
  journal={Clinical otolaryngology and allied sciences},
  year={2003},
  volume={28 1},
  pages={
          39-42
        }
}
Glucocorticoids have been used in the treatment of otitis media with effusion with promising but inconsistent results. The HT29-MTX cell line is a completely differentiated and almost exclusively mucus-secreting goblet cell line. To assess the potential of steroids in suppressing mucin secretion, we have studied the response of this cell culture to prednisolone. Confluent cell cultures were trypsinized, subcultured in six-well plates and incubated with five doses of prednisolone from 10-3 M to… CONTINUE READING
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