Influence of pleural pressure variations on cardiovascular system dynamics: a model study

  title={Influence of pleural pressure variations on cardiovascular system dynamics: a model study},
  author={Yaakov Goldstein and Rafael Beyar and Samuel Sideman},
  journal={Medical and Biological Engineering and Computing},
A mathematical model of the human cardiovascular system (CVS) is used to study the effect of different respiratory manoeuvres on the circulation. The model simulates the normal CVS and the interaction between the heart and the intrathoracic pressure. The vascular system is represented by resistive, capacitive and inertial elements whereas the ventricles are assumed to function according to the time-varying elastance concept based on their transmural pressures. The model predicts that normal… 
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  • E. Goldman
  • Medicine
    American journal of physiology. Heart and circulatory physiology
  • 2010
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