Influence of platelet activating factor on expression of adhesion molecules in experimental pancreatitis.

@article{Zhao2003InfluenceOP,
  title={Influence of platelet activating factor on expression of adhesion molecules in experimental pancreatitis.},
  author={Hua Zhao and Ji-Wei Chen and Ya-Kui Zhou and Xue-feng Zhou and Pei-Yun Li},
  journal={World journal of gastroenterology},
  year={2003},
  volume={9 2},
  pages={338-41}
}
AIM To determine whether Platelet activating factor (PAF) has a regulation role in the expression of adhesion molecules and accumulation of neutrophils in a murine model of acute pancreatitis. METHODS One hundred twenty-eight Kunming mice were divided into four groups. Group 1 received 0.1 ml saline s.c. every hour for three hours (sham). Group 2 received cerulein (50 microg/kg dose s.c.) every hour for three hours. Group 3 received AP and additional challenge of PAF (50 mg/kg in absolute… CONTINUE READING