Influence of pioglitazone on experimental heart failure and hyperlipidemia in rats

@article{Biswas2012InfluenceOP,
  title={Influence of pioglitazone on experimental heart failure and hyperlipidemia in rats},
  author={A. Biswas and S. Rabbani and K. Devi},
  journal={Indian Journal of Pharmacology},
  year={2012},
  volume={44},
  pages={333 - 339}
}
  • A. Biswas, S. Rabbani, K. Devi
  • Published 2012
  • Medicine
  • Indian Journal of Pharmacology
  • Objectives: To investigate the effect of pioglitazone on isoproterenol-induced heart failure and high-fructose diet-induced metabolic changes in rats. Materials and Methods: Three doses of pioglitazone (Pio – 3, 10, 30 mg/kg, po) were tested in male Wistar rats. In the Heart Failure (HF) group, treatment was followed by Isoproterenol (ISO) injection. The markers for HF, such as enzyme estimation, relative heart weight, and antioxidant status, were evaluated. In another group, metabolic… CONTINUE READING