Influence of phospholipid polyunsatured fatty acid composition on some metabolic disorders induced in rat cardiomyocytes by hypoxia and reoxygenation.

@article{Chevalier1990InfluenceOP,
  title={Influence of phospholipid polyunsatured fatty acid composition on some metabolic disorders induced in rat cardiomyocytes by hypoxia and reoxygenation.},
  author={Annie Chevalier and Luc Demaison and Alain Grynberg and Pierre Athias},
  journal={Journal of molecular and cellular cardiology},
  year={1990},
  volume={22 10},
  pages={1177-86}
}
The influence of membrane polyunsaturated fatty acid (PUFA) composition on lactate production, energy status, enzyme leakage and cell defences against oxygen free radical production was studied in cultured rat ventricular myocytes during hypoxia and reoxygenation. After 4 days in a conventional serum-supplemented medium, the cardiomyocytes were incubated for 24 h in synthetic media containing either linoleate and arachidonate (SM6 Medium) or linolenate and eicosapentaenoate (SM3 Medium) as… CONTINUE READING

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