Influence of parenteral administration routes and additional factors on vaccine safety and immunogenicity: a review of recent literature

@article{Herzog2014InfluenceOP,
  title={Influence of parenteral administration routes and additional factors on vaccine safety and immunogenicity: a review of recent literature},
  author={Christian Herzog},
  journal={Expert Review of Vaccines},
  year={2014},
  volume={13},
  pages={399 - 415}
}
  • C. Herzog
  • Published 13 February 2014
  • Medicine
  • Expert Review of Vaccines
Vaccines have to be administered via an appropriate route, i.e. a route, which is optimal regarding safety, immunogenicity and practicability. In addition, there are factors, such as body site, needle length, injection technique, depth of injection, type of antigen, vaccine formulation, adjuvants, age, sex, race/ethnicity, body mass, and pre-existing immunity, which can have an impact on the reactogenicity and tolerability and/or on the immunogenicity of a given vaccine. For parenteral vaccine… Expand

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