Influence of oxidative stress on inducing micturition dysfunction following chronic infravesical obstruction and the protective role of an antioxidant diet - association of in vivo and in vitro studies in rats.

@article{Bisogni2012InfluenceOO,
  title={Influence of oxidative stress on inducing micturition dysfunction following chronic infravesical obstruction and the protective role of an antioxidant diet - association of in vivo and in vitro studies in rats.},
  author={S{\'e}rgio Bisogni and Fabio Thadeu Ferreira and Arnaldo Amstalden Neto and Leandro Oliveira Chiarelli and Valdemar Ortiz},
  journal={International braz j urol : official journal of the Brazilian Society of Urology},
  year={2012},
  volume={38 4},
  pages={552-60}
}
OBJECTIVE This study was developed to determine whether the generation of free radicals, induced by ischemia followed by reperfusion in a model of chronic intravesical obstruction in rats, would lead to damage in the detrusor. It also investigates the possible protective action of the flavonoid galangin on the tissue lesion induced by lipid peroxidation. MATERIALS AND METHODS Twenty-one male rats were divided into three groups of seven animals each. Group A was subjected to a sham procedure… CONTINUE READING

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